Traditional Chinese Medicine (TCM) has a 3000 years’ history of human use. A literature survey addressing traditional evidence from human studies was done, with key result that top 10 TCM herb ingredients including Poria cocos, Radix polygalae, Radix glycyrrhizae, Radix angelica sinensis, and Radix rehmanniae were prioritized for highest potential benefit to dementia intervention, related to the highest frequency of use in 236 formulae collected from 29 ancient Pharmacopoeias, ancient formula books, or historical archives on ancient renowned TCM doctors, over the past 10 centuries. Based on the history of use, there was strong clinical support that Radix polygalae is memory improving. Pharmacological investigation also indicated that all the five ingredients mentioned above can elicit memory-improving effects in vivo and in vitro via multiple mechanisms of action, covering estrogenlike, cholinergic, antioxidant, anti-inflammatory, antiapoptotic, neurogenetic, and anti-Aβ activities. Furthermore, 11 active principles were identified, including sinapic acid, tenuifolin, isoliquiritigenin, liquiritigenin, glabridin, ferulic acid, Z-ligustilide, N-methyl-beta-carboline-3-carboxamide, coniferyl ferulate and 11-angeloylsenkyunolide F, and catalpol. It can be concluded that TCM has a potential for complementary and alternative role in treating senile dementia. The scientific evidence is being continuously mined to back up the traditional medical wisdom.
In the vast tapestry of existence, there's a delicate play between yin and yang. It's like the ebb and flow of tides on a restless shore, a dance of opposites in the grand ballroom of life. Yin, it's the cool shade of an ancient tree, the quiet hush of a tranquil night. It's the essence of receptivity, a hidden power that nurtures and cradles, like a mother's embrace in the hush of twilight. Yang, it's the fiery sun that paints the sky with its golden touch, the vibrant hum of a bustling city. It's the force of action and assertion, the spark that drives life forward, like a river's current carving its path through unyielding stone. In the world of yin and yang, it's all about balance, a dance of harmonies that shape the world around us. Too much yang, and the flames of chaos might consume everything in their path. Too much yin, and the world might slip into a silent slumber, its vitality smothered. Life's canvas is painted with strokes of both, ...
Comments
Post a Comment