Traditional Chinese Medicine (TCM) has a 3000 years’ history of human use. A literature survey addressing traditional evidence from human studies was done, with key result that top 10 TCM herb ingredients including Poria cocos, Radix polygalae, Radix glycyrrhizae, Radix angelica sinensis, and Radix rehmanniae were prioritized for highest potential benefit to dementia intervention, related to the highest frequency of use in 236 formulae collected from 29 ancient Pharmacopoeias, ancient formula books, or historical archives on ancient renowned TCM doctors, over the past 10 centuries. Based on the history of use, there was strong clinical support that Radix polygalae is memory improving. Pharmacological investigation also indicated that all the five ingredients mentioned above can elicit memory-improving effects in vivo and in vitro via multiple mechanisms of action, covering estrogenlike, cholinergic, antioxidant, anti-inflammatory, antiapoptotic, neurogenetic, and anti-Aβ activities. Furthermore, 11 active principles were identified, including sinapic acid, tenuifolin, isoliquiritigenin, liquiritigenin, glabridin, ferulic acid, Z-ligustilide, N-methyl-beta-carboline-3-carboxamide, coniferyl ferulate and 11-angeloylsenkyunolide F, and catalpol. It can be concluded that TCM has a potential for complementary and alternative role in treating senile dementia. The scientific evidence is being continuously mined to back up the traditional medical wisdom.
In Five Element Acupuncture, the term "perverse energy" refers to an abnormal or disharmonious flow of energy within the body and its meridians (energy channels). It represents an imbalance or disruption in the natural circulation of Qi (vital energy) through the elemental pathways. Perverse energy can manifest in various ways, such as excessive or stagnant energy, energy flowing in the wrong direction, or energy being blocked or dispersed improperly. It is considered to be a deviation from the healthy and balanced flow of energy that supports overall well-being. When perverse energy occurs, it can disrupt the functioning of organs, meridians, and the mind, leading to physical symptoms, emotional imbalances, and a general sense of unwellness. It is believed to be influenced by factors such as lifestyle, emotions, external pathogens, or constitutional weaknesses. The concept of perverse energy is important in Five Element Acupuncture because it helps identify and address und...
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